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A short history of the evolution of surgery
László Damjanovich Professor of Surgery
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Evolution of surgery Introduction to modern surgery Short history of the Medical School of Debrecen and the Surgical Institute
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„The abdomen, the chest and the brain will forever be shut from the intrusion of the wise and humane surgeon.”Sir John Ericksen, Surgeon Extraordinaire to Queen Victoria, 1837
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„Today our colleagues perform an average of 80.000 operations each day (in the USA), many in the abdomen, chest or brain” Daniel J. Riskin, UCLA, 2006
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Epochs of Surgery
Characteristics of the pre-modern phase: Lack of significant anatomical knowledge Progress was made by the isolated achievement of outstanding personalities Methods were tested during major wars under the pressure of necessity Clerical dogmas prevailed over scientific contributions
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Medical heritage of early civilizations
The earliestwrittenpiece of medicalhistory, 1600-1500 B.C. Edwin Smith Egyptianpapyrus: surgerywaswelldefined, havingimportantroleinmedicine containscasereportsin a logicallyarranged series personalcleanliness, hygiene and correctdiagnosisbeforetreatmentwasimportant
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Scope of surgical activities
Bandages, dressings Circumcision Opening abscesses Fractures, dislocations Lithotomies (urolith) Hemorrhoides, fistulas Amputations Tooth extractions Herniotomies
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Hippocrates(460-375 b.c.)
„The father of medicine” Medicine and surgerywasonediscipline Great attentiontoobservation, detail, recordkeeping, gatheringknowledgeaboutdiseases, cleanliness, order, practice „Humoralpathology” Corpus Hippocraticum, devotiontothepatient,
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Ancient textbooks
AyurVeda(The book of life) India, China Code of Hammurabi2000 B.C. Mesopotamia)(Surg., Medical, Legal text) Alexandria: Aristotle, Herophilos, Erasistratos Roman empire: Celsus 8 books, Galenus (treatedgladiators, dissectedpigs, manyerrors, greatimpactuntil XV. century, disagreementwasheresy) Arabicperiod, Avicenna(Persian) Xthcentury: The Canon (surgeryas a necessaryevil, Baghdad, Damascus, Cairo: hospital-med. schools)
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Medieval medicine (476-1453)
Religiousmedicine, dogmas Lowsocial status of surgeons Surgerypracticedbybarbersurgeons Clericalbanonautopsies, absense of anatomicalknowledge (dissectiononpigs) Miracles made bysaints Illnes is a retributionfromheaven Hospitalsmaintainedbythechurch The sicktakencare of bynuns
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The Salerno School
Firstschool of formaltraining,commencedinthe 12th century, southernItaly The firstsecularmedicalschool Revival of ancientknowledge Dissectiononpigs More emphasisonsurgery Recordingownexperience of surgeons Roger of Salerno: CyrurgiaRigerii 1170- thefirstindependentsurgicalworkinthe West The schoolmovesto Bologna afterhisdeath
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Development of medicine in the middle ages
Lanfranc 1315. France, against „pusbonum et laudabile” keepitclean Pope SixtusIV. (1414-1484) appr. autopsies, stimulation of studies Leonardo da Vinci, Michelangelo, Dürer, Titian… Jacob Sylvius, Paris: Galen’sanatomy Andreas Vesalius, Brussels: atage 23, professor of surgery De Humani Corporisfabrica (atage 28) Paracelsus, Basel: „internalmedicine and surgery must not be separated”
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Ambroise Paré 1510-1590
Apprentice of Vesalius FieldsurgeonintheFrencharmy Performedautopsies Usedturpentine, instead of burningoiltotreatgunshotwounds, amputatedlimbs Routineligature of vessels Inventednewinstruments, limbprostheses
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XVIII. Enlightenment
Revival of ancientmedicalknowledge William and John Hunter Anatomy of thegraviduterus (William) Ligature of theaneurysmofthesuperficialfem. art. (instead of amputation) infourcasessuccesfully Angina pectorisinhisowncase (John)
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Beginning of modern surgery
Phase I: introduction of anaesthesia (Morton) anesthetic – theagent 1842. January: William E. Clarke toothextractionunderethernarcosisRochester, NY 1846. October: Dr.John C. Warren (NEJM, AMA, 1stdean of Harvard)jaw tumor removalunderethernarcosisperformedby William T.G. Morton
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Warren and Morton
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Early development of biomedical sciences
Edward Jenner (surgeon): 1749-1823 Vaccination, pox Theodor Schwann: 1810-1882, cells Rudolf Virchow 1821-1902, cellularpathology Francois Magendie 1783-1855, nervoussystemanatomy Claude Bernard 1813-1878, experimentalphysiologyhomeostasis
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Antisepsis-asepsis, II. phase
Louis Pasteur: correlationbetweenrotting and oxygencontent of the air, discovery of bacteria Joseph Lister: carbolicacidusedforsanitationinCarlisle, woundtoilette, and operatinginstruments, deathratedroppedto 1/3, lead and zincplatestocoverwounds Semmelweis Ignácz: hypochloricacidfordecontamination of thehandafterautopsies R.Koch: TB, anthrax, steemforsterilization Trendelenburg, Schimmelbusch: steamsterilization Steril rubbergloves: Halsted 1891. Facemask: Hunter 1900.
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The first(surgical) Nobel Prizeinmedicine
Theodor Kocher1841-1917. Bern 1909: „…forhisworkinphysiology, pathology and surgeryonthethyroidgland…”
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Features of modern surgery
Highdegree of specialization (heart, vascular, chest, pediatric, colorectal…) Maximum use of relatedsciences (rtg, US, CT, MRI, laboratorytests, endoscopy…) Fast and wideshare of information Research orienteddevelopment of surgeryguidedbytherules of science and law and grants!
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Independent disciplines sprouting from general surgery
Urology Orthopedics Radiology Traumatology Chest surgery Heart surgery Pediatric surgery Hand surgery Vascular s. Transplantation s. Neurosurgery Head and neck s. Ophtalmic s. Plastic s.
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Cooperation between disciplines
„ClinicalSciences” Anesthesiology, ICU Imaging: US, CT, MR, PET, nuclearmedicine Laboratorydiagnostics, microbiologylab Internalmedicine (gastroent., endocrin., cardiol., nephrol…) Surgery TheoreticalSciences” Anatomy, physiol., chemistry, physics Pharmacology Engineering (sterilization, lighting, laparoscopy, endoscopy, US cuttingdevices, staplers, implants Immunology (transfusion, transplantation…) Genetics (FAP, HNPCC…)
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Science Art, Personalchallenge Handicraft Surgery
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Historical moments of the University of Debrecen
Calvinist Coll. 1541 University XVII th century 1750- István Hatvani: naturalsciencesinthecurricula 1906. Gyula Kenézy, theol., law, science and medicalfaculties 1914-1918. University of Arts and Sciences, FlorisKorb 1921: Inauguration of theMedicalFaculty Four out of 15 professorsstayin Debrecen duringWWII 1951: Med. Fac. becomes and independentuniversity: DOTE 1977: DentistryFac. founded 1987: English Program initiated 1998: University Assoc. of Debrecen DATE, DOTE, KLTE, KFRTF, LFZFDK, ATOMKI, DRHE 2000: UDMHSC
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Prof. Tivadar Hüttl
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